About I-Know
I-Know is a knowledge discovery IT -based tool designed to aid early stroke diagnosis, stroke treatment, drug development and identification of risk factors as targets in disease prevention for the benefit of European industry and citizens.
Acute stroke is a major socioeconomic burden in EU. The disabilities following the disease develop rapidly and prompt treatment of patients is imperative. Currently a drug dissolving the blood clot (rtPA – thrombolysis) is the only established treatment, but this is only implemented at highly specialised centres. There is consequently a st
At the same time there is an intense search by pharmaceutical industry and academic biomedical research to identify drugs that will stop the tissue damage progressing after acute stroke.
Through computerized stroke disease progression models (DPMs), I-Know will provide an accurate diagnosis in individual patients (based on patient history and genetic profile, biochemical, clinical and neuroimaging findings). Interacting with the physician, I-Know will produce images, predicting the course of the disease given available therapeutic options and their specific actions recorded in other patients (DPMs from clinical trials). In a system seamlessly integrated with eHealth systems, this allows physicians to diagnose and treat the patient on the basis of a wealth of information otherwise impossible to integrate by the human mind.
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